Archive

Author: Anand Swaminathan

Initial Antibiotic Choice in Uncomplicated Cellulitis

Background: Cellulitis is a common emergency department (ED) presentation. Despite the fact that diagnosis remains relatively straight forward, complexity remains in management in terms of the causative agent and appropriate antibiotic regimen. Though beta-hemolytic Streptococci are the most common causative ...

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Infectious Disease

Should You Give Albumin in Spontaneous Bacterial Peritonitis (SBP)?

The Background: Nearly 50% of patients in the U.S. with cirrhotic liver disease develop ascites over a 10-year period of observation, placing them at risk for developing spontaneous bacterial peritonitis (SBP) (Runyon 2012). It is estimated that 12-25% of patients with ...

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Infectious Disease

The WOMAN Trial: Early TXA in Post-Partum Hemorrhage

Background: Post-partum hemorrhage (PPH) is the leading cause of maternal death worldwide. It is typically defined as > 500 ml of blood loss within 24 hours of giving birth. However, PPH encompasses a broad spectrum of disease from mild oozing ...

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Obstetrics and Gynecology

Local Anesthetic Systemic Toxicity (LAST)

Definition: A life-threatening adverse reaction resulting from local anesthetic reaching significant systemic circulating levels. Local Anesthetic Systemic Toxicity (LAST) is rare and almost always occurs within minutes of injection of the local anesthetic. Causes: Injection of local anesthetic into the ...

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Toxicology

Validation of the Step-By-Step Approach to Febrile Infants

Background: Fever without source in infants less than three months old presents a difficult diagnostic dilemma for ED physicians.  Over the past 25 years several algorithms have been developed to help guide clinicians, most notably the Rochester, Philadelphia and Boston ...

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Pediatrics

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