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Tag: Topical Tranexamic Acid

Topical TXA in Atraumatic Anterior Epistaxis Yet Again

Background: The use of topical tranexamic acid (TXA) for anterior epistaxis has been studied in many trials with conflicting results. The largest and most methodologically rigorous study to date on the use of topical TXA in epistaxis has been the …

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Head, Eye, Ear, Nose, and Throat

Classic Journal Club: TXA for Epistaxis

Background: Epistaxis is a common ailment experienced by millions worldwide. While most of these cases can be managed by patients at home, some will require medical attention. Initial interventions include local pressure, ice, and forward head positioning for persistent bleeds. When …

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Head, Eye, Ear, Nose, and ThroatHematology and Oncology

Meta-Analysis on Topical TXA for Epistaxis

Background Information: Epistaxis management in the emergency department has historically included topical vasoconstrictors, local anesthetics such as oxymetazoline and phenylephrine and topical fibrinolytic agents such as Tranexamic Acid (TXA). When these topical agents fail, packing, chemical cauterization or surgical ligation …

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Head, Eye, Ear, Nose, and ThroatProcedures and SkillsResuscitation

REBEL Cast Ep97: The NoPAC Trial – TXA for Epistaxis?

Background: Epistaxis is a common Emergency Department (ED) complaint with over 450,000 visits per year and a lifetime incidence of 60% (Gifford 2008, Pallin 2005). Standard anterior epistaxis treatment consists of holding pressure, use of local vasoconstrictors, topical application of …

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Head, Eye, Ear, Nose, and Throat

Topical Tranexamic Acid for Epistaxis or Oral Bleeds

Recently, there has been a lot of buzz about the use of topical tranexamic acid for epistaxis or oral bleeds on multiple social media platforms. Everyone seems so happy that it works so well, but we thought we would look through …

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Head, Eye, Ear, Nose, and ThroatHematology and Oncology

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