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Tag: COVID-19

The RECOVERY Trial: Tocilizumab

Background: Publication of the RECOVERY trial results on Dexamethasone were game changing – the drug had a clear reduction in mortality in patients requiring oxygen. Since then, we have had little to celebrate in terms of therapeutics in those with …

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Infectious Disease

BLAZE-1 Final Publication: Monoclonal Antibody Cocktail Part II

Background: One of the many massive challenges of the COVID19 pandemic has been the lack of targeted therapeutics. Extensive efforts have been invested into research with only glimmers of benefit for most drugs. The exception to this has been dexamethasone …

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Infectious Disease

COVID-19 Awake Proning – All Hype?

Background: Facilities around the world have seen surges of COVID-19 pneumonia  patients who have required protracted hospitalizations leading to overwhelmed hospital systems. Awake proning is a practice that was adopted early in the pandemic as a means to avoid, or …

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Infectious DiseaseThoracic and Respiratory

COVID-19 Update: The ChAdOx1 (AstraZeneca) COVID-19 Vaccine

Background Information: With rising cases, an increasing death toll, and a significant strain on hospital systems globally, the COVID-19 pandemic seemed to have no end in sight. The aggressive pursuit of a vaccine has led to multiple clinical trials starting before …

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Infectious Disease

REBEL Cast Ep93: COVID-19 – A Follow Up on Not Intubating Early and ARDSnet

Back in April 2020, on REBEL Cast episode 79 we sat down to discuss COVID-19.  Specifically, we focused on not intubating patients early and why ARDSnet may not be the best ventilator paradigm for patients with COVID-19.  By popular demand, …

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Infectious Disease

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