Archive

Medical Category: Thoracic and Respiratory

GLUCOCOVID: A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia

Background Information: The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and Middle Eastern Respiratory Syndrome have ...

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Infectious DiseaseThoracic and Respiratory

REBEL Review 101: Richmond Agitation-Sedation Scale (RASS)

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REBEL Reviews

The HOT-ICU Trial: Lower vs Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

Background: Though oxygen is fundamental for life, supra-physiological levels can be deleterious. Several randomized controlled trials and meta-analyses have been conducted in the critically ill to determine whether a conservative oxygenation approach compared to a liberal oxygenation approach is beneficial. ...

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Thoracic and Respiratory

The RELAx Trial: What is the Optimal PEEP in Patients Without ARDS?

Background: It has well been established that low tidal volume ventilation minimizes potentially iatrogenic harms of mechanical ventilation.  What is less clear is the use of higher positive end expiratory pressure (PEEP) in patients without acute respiratory distress syndrome (ARDS). ...

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Thoracic and Respiratory

COVID-19 Awake Proning – All Hype?

Background: Facilities around the world have seen surges of COVID-19 pneumonia  patients who have required protracted hospitalizations leading to overwhelmed hospital systems. Awake proning is a practice that was adopted early in the pandemic as a means to avoid, or ...

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Infectious DiseaseThoracic and Respiratory

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