Archive

Medical Category: Neurology

The ESETT Trial: 2nd Line Medications in Status Epilepticus

Background: Dealing with a patient in status epilepticus, refractory to treatment with benzodiazepines, can be a sphincter tightening ordeal.  While most seizure activity responds to appropriately dosed benzodiazipines, some will not respond. The choice of second line medication has been ...

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Neurology

REBEL Core Cast 24.0 – Stroke Update 2019

Take Home Points Important as front line providers to know research and data behind stroke care Patients eligible for endovascular care are those with large vessel occlusion in the anterior circulation – anterior cerebral artery, middle cerebral artery, distal intracranial ...

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Neurology

REBEL Cast Ep72: Systemic Alteplase in Stroke Mimics is Safe?

Background: Currently, alteplase is the mainstay of treatment of acute ischemic stroke.  Advocates of alteplase suggest that the benefit of alteplase is greatest when given early and declines with increasing time from stroke symptom onset (i.e. time is brain).  Therefore, the ...

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Neurology

Rimegepant and Inflammatory Neuropeptide Antagonism in Migraine

Background: Migraine is a chronic neurologic disease characterized by attacks of throbbing, often unilateral headache that are exacerbated by physical activity and associated with photophobia, phonophobia, nausea, vomiting, and, in many patients, cutaneous allodynia. Migraine is very common, and the burden ...

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Neurology

REBEL Cast Episode 67: EXTEND-ing Times for Systemic Thrombolysis in Acute Ischemic Stroke?

Background: Despite the lack of replication of the NINDS & ECASS-3 trials, guidelines recommend the use of tPA in the ≤4.5hr window after the onset of symptoms of acute ischemic stroke . These recommendations used non-contrast computed tomography (NCHCT) for the ...

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Neurology
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