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Tag: Toxicology

REBEL Core Cast 5.0 – Accidental Hypothermia

Take Home Points: Hypothermia is neuroprotective and patients can survive prolonged periods of cardiac arrest. Termination of resuscitative efforts in cardiac arrest should not considered until the patient is >32°C or has a K > 12 mEq/L Active internal rewarming …

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Environmental

The HOUR Trial: Clinical Decision Rule for Opioid Overdose Patients in the Emergency Department

Background Information: In 2017, more than two-thirds of the 70,000 drug overdose deaths in the United States involved an opioid.1 Many emergency departments are affected as opioid overdoses increased 30% from July 2016 through September 2017 in 52 areas in …

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Toxicology

Journal Abstracts and Why You Should Continue to Use Phenobarbital in Alcohol Withdrawal Syndrome for Patients Requiring Admission

Background: The mainstay of treatment for alcohol withdrawal syndrome is a symptom-triggered approach using benzodiazepines. Phenobarbital, however, is an interesting agent in this scenario for several reasons. It is famous for  it is long duration of action. IV Phenobarbital has an …

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Toxicology

Salicylate Toxicity

Definition: Salicylate toxicity is characterized by a constellation of symptoms caused by acute or chronic overdose of salicylate containing compounds. The most common salicylate is aspirin, but the group also includes topical forms of salicylates, methyl salicylate (Oil of Wintergreen), …

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Toxicology

Wernicke Encephalopathy

Definition: Encephalopathy that occurs secondary to thiamine (vitamin B1) deficiency. While Wernicke encephalopathy is reversible with treatment, it can progress to the irreversible Korsakoff’s syndrome if left untreated.

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Toxicology

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