Archive

Tag: Sepsis

Is Pip-Tazo Harming Sepsis Patients?

Background: Patients with sepsis are routinely treated with empiric broad-spectrum antibiotics while awaiting source identification, as recommended by the surviving sepsis campaign.2 Vancomycin, in combination with either piperacillin-tazobactam or cefepime, is commonly used for empiric treatment in these cases. Literature ...

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Infectious Disease

The ACORN Trial: Battle of the Gorilla-Cillins (Cefepime vs Piperacillin-Tazobactam)

Background: Acutely ill adults presenting to the hospital with suspected infection commonly receive empiric, broad-spectrum antibiotics as part of their initial management including coverage of both MRSA and pseudomonas species.  MRSA coverage includes the use of vancomycin while anti-pseudomonal coverage ...

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Infectious Disease

Pre-Hospital Antibiotics in Sepsis?

Background: Sepsis remains one of the leading causes of morbidity and mortality. It is well-established that earlier recognition and treatment can lead to better outcome for these patients .  Time to antibiotic therapy (from triage, not from onset of infection) has ...

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Infectious Disease

Congestive Heart Failure and Sepsis: A Closer Look at Fluid Management

Background: In medicine, guidelines are valuable tools that help guide care. However, they are not rigid rules that must be strictly followed. Clinicians often find themselves grappling with the challenge of balancing the demands of meeting Center for Medicaid & ...

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Infectious DiseaseResuscitation

An Herbal Hope: Is XBJ A Game-Changer in Sepsis Management?

Background: Could Xuebijing (XBJ) catalyze a paradigm shift in sepsis management? XBJ is an herbal compound used in China to manage various inflammatory and infectious processes in recent years, including sepsis.2-6 It is an herbal preparation comprising a blend of ...

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Resuscitation

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