Ondansetron Archives - REBEL EM - Emergency Medicine Blog

Do Ondansetron Prescriptions Reduce Pediatric Return Visits for Nausea and Vomiting?

by Jenny Beck-Esmay, MD posted October 22, 2020 No Comments

Background: Acute gastroenteritis (AGE) is a very common emergency department (ED) presentation, with “approximately 1.5 million pediatric outpatient visits and 200,000 admissions” each year (Benary). Treatment for AGE is mainly supportive, utilizing rehydration therapy and antiemetic medications. One common and …

Abdominal and GastroinstestinalPediatrics

Association of Maternal First-Trimester Ondansetron Use with Cardiac Malformations and Oral Clefts in Newborns

by Mark Ramzy posted April 16, 2020 No Comments

Background Information: Nausea and vomiting during pregnancy most commonly occurs during the first trimester. If left untreated, the development of hyperemesis gravidarum can lead to further complications characterized by dehydration and electrolyte abnormalities.1 Ondansetron, a 5-HT3 receptor antagonist has quickly …

Obstetrics and GynecologyToxicology