Archive

Tag: Ondansetron

Clinical Conundrum: Pregnant and Puking: What’s Safe and Effective in the ED?

Nausea with or without vomiting is very common in early pregnancy, affecting approximately 70% of pregnancies (Maisal 2012). Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy that can lead to significant maternal dehydration, electrolyte abnormalities, and ...

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Obstetrics and Gynecology

REBEL Core Cast 145.0: Understanding QTc Prolongation: Causes, Risks, and Management

The QT interval is a vital part of ECG interpretation, reflecting the heart’s electrical recovery after each beat. When prolonged, it can set the stage for torsades de pointes. Understanding how to measure and correct the QT interval, identify high-risk ...

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Procedures and SkillsResuscitation

Do Ondansetron Prescriptions Reduce Pediatric Return Visits for Nausea and Vomiting?

Background: Acute gastroenteritis (AGE) is a very common emergency department (ED) presentation, with “approximately 1.5 million pediatric outpatient visits and 200,000 admissions” each year (Benary).   Treatment for AGE is mainly supportive, utilizing rehydration therapy and antiemetic medications.  One common and ...

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Abdominal and GastrointestinalPediatrics

Association of Maternal First-Trimester Ondansetron Use with Cardiac Malformations and Oral Clefts in Newborns

Background Information: Nausea and vomiting during pregnancy most commonly occurs during the first trimester. If left untreated, the development of hyperemesis gravidarum can lead to further complications characterized by dehydration and electrolyte abnormalities.1 Ondansetron, a 5-HT3 receptor antagonist has quickly ...

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Obstetrics and GynecologyToxicology

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