Tag: Hypertonic saline

Let’s Get Salty: Hypertonic 3% Saline Through Peripheral IVs in Adult Patients with Traumatic Brain Injury

by Salim Rezaie posted March 14, 2024 No Comments

Background: Elevated intracranial pressure in patients with acute brain injury is a neurologic emergency requiring early recognition and early aggressive treatment to prevent progression to cerebral ischemia, brain herniation, and ultimately death. There are two primary options for treatment in …

NeurologyTrauma

The SALSA Trial: Symptomatic Hyponatremia and Hypertonic Saline

by Salim Rezaie posted May 6, 2021 No Comments

Background: Hyponatremia is one of the most common electrolyte abnormalities seen in clinical practice. Under-correction could lead to cerebral edema, whereas overcorrection could result in osmotic demyelination syndrome (ODS). The current recommendation is to use hypertonic saline in small, fixed, …

Endocrine, Metabolic, Fluid, and Electrolytes