Tag: Dexmedetomidine

Effect of Sepsis Bundle (SEP-1) Compliance and Implementation on Mortality

by Melissa Smith, MD, RN and Maren Leibowitz, MD posted August 24, 2026 No Comments

Is there any moderate or high-level evidence that SEP-1 compliance and/or implementation is associated with improvement in sepsis mortality?

Infectious DiseaseResuscitation

SPICE III Trial: Does Early Dexmedetomidine Improve Survival in Mechanically Ventilated ICU Patients?

by Dorian Alexander, MD posted August 17, 2026 No Comments

Is HFNC as effective as NIV in reducing respiratory rate and improving respiratory distress within 2 hours in ACPE?

Neurology

The MENDS2 Trial: Dexmedetomidine vs Propofol for Sedation

by Salim Rezaie posted April 15, 2021 No Comments

Background: In patients requiring mechanical ventilation, sedative medications are used for patient comfort and safety. However, these medications can also lead to brain dysfunction (i.e. delirium or coma) and long-term cognitive impairment. Currently, the Society of Critical Are Medicine ...

Thoracic and Respiratory

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