Archive

Tag: COVID-19

Hydroxychloroquine is Ineffective for Post-Exposure Prophylaxis

Background: Despite the initial excitement around the use of chloroquine (CQ) and hydroxychloroquine (HCQ), there is mounting evidence that neither drug is effective in COVID-19 treatment. Laboratory studies have shown antiviral and immunomodulatory properties in vitro but these have not …

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Infectious Disease

Convalescent Plasma Therapy for COVID-19: Hopeful Signals of Improvement

Background: Convalescent plasma therapy is not a new or novel therapeutic option.  It involves taking the plasma from patients who have recovered from an illness and using it to treat patients who currently have the same illness. This approach has …

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Infectious Disease

COVID-19: Remdesivir RCT #3 (5d vs 10d)

Background: We have covered the two previous RCTs on remdesivir on REBEL EM (RCT #1 and RCT #2). In the first trial by Wang et al [2], there was no statically significant improvement in clinical outcomes, but, there were trends …

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Infectious Disease

REBEL Cast Ep83 – COVID-19 in the ICU, ECMO Early, & Steroids with Jeff Dellavolpe, MD

I am fortunate to work in a hospital system that is very forward thinking.  We have a phenomenal relationship with our intensivists, and I have been fortunate enough to have several discussions with them about how we are managing COVID-19 …

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Infectious DiseaseResuscitationThoracic and Respiratory

COVID-19: IMV and Mortality at Emory

Background: One of the hot topics in COVID-19 care is the mortality rate associated with invasive mechanical ventilation (IMV). There have been early reports of IMV having mortality rates ranging from 50 to 90%.  These high rates are concerning but, …

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Infectious DiseaseThoracic and Respiratory

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