Archive

Tag: COVID-19

The DANMASK-19 Trial: Masks Not Effective to Prevent COVID-19? Not So Fast!!!

Background: Face masks can reduce transmission of respiratory viruses by both being a potential physical barrier and by reducing droplet transmission.  Additionally, the presence of a mask reduces the users frequency of touching their face which may also reduce transmission.  ...

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Infectious Disease

A COVID-19 Update that is Long Overdue

Background: There have been lots of trials sitting on my computer desktop awaiting my review, but like many of you time has been thin from clinical work and increasing cases of COVID-19 where I work.  I thought it might be ...

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Infectious Disease

COVID-19: An EBM Take

The Novel Coronavirus 2019, was first reported on in Wuhan, China in late December 2019.  The outbreak was declared a public health emergency of international concern in January 2020 and on March 11th, 2020, the outbreak was declared a global ...

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Infectious Disease

US Expanded Access Program: Convalescent Plasma, Mortality, and COVID-19

Background: Convalescent plasma therapy (CPT) is not a novel treatment modality.  It has been used in other illnesses such as SARS, MERS, and Ebola with variable results. The theory behind CPT is to take antibody rich blood from patients who ...

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Infectious Disease

Remdesivir in Moderate COVID-19

Background: There are three randomized clinical trials now published on remdesivir in the treatment of COVID-19 pneumonia (RCT 1, RCT 2, & RCT 3). The 1st trial, performed in China, was terminated early due the lack of patients to enroll ...

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Infectious Disease

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