April 28, 2020

Early reports have shown that COVID-19 is most likely causing a hypercoagulable state, however the prevalence of acute VTE and exactly how to treat it is an evolving area.  Limited data suggest pulmonary microvascular thrombosis may play a role in progressive respiratory failure.  However, most evidence is limited to small retrospective trials.  As we wait for more evidence, clinical decisions have to made at the bedside and decisions about pharmacological prophylaxis are starting to emerge.  In this episode I sit down with a special guest that is new to REBEL Cast to talk about the dilemmas involving COVID-19 and thrombosis.

April 26, 2020

Background: Awake proning, or having patients lie on their stomachs, can help oxygenation by helping to recruit posterior portions of the lungs and by helping with perfusion to oxygenated lung segments. The literature around proning centers on intubated patients with adult respiratory distress syndrome in the ICU. However, there are increasing recommendations from front line clinicians and experts about the benefits of proning hypoxemic COVID19 patients who are awake in an effort to improve oxygenation and stave off intubation. While there may be physiologic reasoning, anecdotal experience and application of data from intubated patients, there is an absence of data specifically on COVID19 patients and proning. Fortunately, we now have some literature to look at:

April 24, 2020

In this episode of REBEL Cast,I sit down with Richard Levitan and talk about some ideas from his experience in New York, where he spent 10 days during the surge of the COVID-19 pandemic. And the lessons he took away were, I think, invaluable for how we’re going to manage these patients going forward.

April 19, 2020

Many facilities are using COVID-19 screening protocols to determine how to cohort patients in the ED. Although this sounded like a good idea initially, this strategy is destined to fail.  Early on in the pandemic, we thought we could identify potential COVID-19 patients based on the presence of fever and cough. However, multiple studies are coming out showing a high prevalence of asymptomatic patients with positive tests for SARS-CoV-2.  Identifying asymptomatic patients is important to improve outpatient quarantine (i.e. maximize physical distancing) and to improve staff safety (i.e. incorrectly admitting patients to the wrong area of the hospital). In most regions, there are simply not enough tests to test everyone, but a universal testing strategy needs to be implemented, especially for admitted patients as this can have major ramifications to staff and patient safety.

April 17, 2020

There are lots of mixed messages flying around social media about COVID-19 lung injury.  Although social media is a very powerful way to get information across, it can also amplify messages that are incorrect or not based in quality research and data.  Two pervasive messages have been that COVID19 lung injury is the same as high altitude pulmonary edema (HAPE) and that COVID19 pneumonia is simply typical acute respiratory distress syndrome (ARDS).
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