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Rebel Category: REBEL Crit

RENOVATE Trial: HFNC vs BPAP in Acute Respiratory Failure

With high flows, modest PEEP, and effective dead-space washout, HFNC can improve oxygenation and decrease work of breathing while preserving the ability to talk, cough, eat, and interact with staff and family. The RENOVATE trial set out to answer a ...

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ResuscitationThoracic and Respiratory

The RSI Trial: Ketamine vs Etomidate in Rapid Sequence Intubation

Etomidate or ketamine? The debate over the ideal agent for emergency rapid sequence intubation (RSI) has raged for years with no clear winner. Etomidate has been touted in the past for its rapid onset and minimal intrinsic effects on hemodynamics. ...

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ResuscitationThoracic and Respiratory

POCUS Use in Shock Resuscitation: Evidence for Patient and System-Level Benefits

Shock is a life threatening condition that requires rapid resuscitation, and targeted treatment. Due to its complex nature, shock management poses many challenges for physicians in the acute care setting, more specifically, in the emergency department (ED). Point-of-care-ultrasound (POCUS) has ...

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CardiovascularResuscitationThoracic and Respiratory

Is Abelacimab the Next Step in AF Anticoagulation? Early Signals and Remaining Questions

Antithrombotic therapy is a cornerstone in the treatment of atrial fibrillation (AFib), though it carries a significant risk of bleeding. While Vitamin K antagonists (VKAs), the oldest anticoagulants, were largely supplanted by direct oral anticoagulants (DOACs) following trials like ARISTOTLE ...

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Cardiovascular

The Dilt Drop: Can Calcium Break the Fall?

Atrial fibrillation with rapid ventricular response (AF with RVR) is one of the most common dysrhythmias encountered in the emergency department and often requires prompt rate control. Diltiazem remains a go-to agent due to its rapid onset, AV nodal selectivity, ...

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Cardiovascular

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