Archive

Author: Anand Swaminathan

PRISMS Trial: Alteplase vs. Aspirin in Minor Stroke

Background: Despite serious concerns about the role of alteplase in the management of acute ischemic stroke including, but not limited to, significant conflicts of interest, unbalanced baseline patient characteristics, systematic devaluation of contrary data, lack of reproduced benefit and low …

Read More
Neurology

Classic Journal Review – Wells + Dimer to Rule Out PE

EM Journal Update: Safety of Using Wells’ Clinical Model With D-Dimer To Manage Patients In The ED With Suspected Pulmonary Embolism Background: In the US, pulmonary embolism (PE) kills 100,000 people each year and over 360,000 new cases of PE …

Read More
Thoracic and Respiratory

Edoxaban in Cancer-Associated VTE

Background: Venous thromboembolism (VTE) occurs frequently in patient with cancer. Treatment in this group entails a number of challenges including a higher rate of thrombosis recurrence and a higher risk of bleeding. Standard therapy at this time for both symptomatic …

Read More
Hematology and Oncology

Cervical Spine Evaluation and Clearance in the Intoxicated Patient

Background: Alcohol and drug intoxication is common in trauma patients and a significant proportion of cervical spine (c-spine) injuries occur in patients with intoxication. A standard approach to both intoxicated and sober patients with suspected c-spine injury in many trauma centers …

Read More
ToxicologyTrauma

Comparison of IM Midazolam, Olanzapine, Ziprasidone and Haloperidol for Behavioral Control

Background: Emergency providers frequently care for agitated patients ranging from restlessness to verbally and physically aggressive. Agitation is a symptom, not a diagnosis and these patients require careful evaluation to rule in or out serious medical conditions. Unfortunately, the agitation itself …

Read More
Pyschobehavioral

Sponsored