Background: The only well-established treatments for sepsis and septic shock are antibiotic therapy and source control. Septic shock, the most severe form of sepsis, is characterized by circulatory and cellular metabolism abnormalities. There have been a host of randomized controlled …
Background: Though it’s been stated numerous times on this blog, it bears repeating: the pillars of sepsis care remain early identification of sepsis, early appropriate empiric antibiotics, source control, and supportive care. The focus should be on getting the basics …
Background: In end-stage renal disease (ESRD) patients on hemodialysis (HD), infection is the second most common cause of mortality after cardiovascular disease (Sarnik 2000). Because of the systemic inflammation and increased capillary permeability, septic patients are at significant risk for fluid …
Background: Getting the basics right in all illness is vital. In sepsis, this means appropriate use of antibiotics, judicious fluid resuscitation, and early identification. Vasopressor support is also essential in the sickest sepsis patients (i.e. septic shock). Should the metabolic …
“You’re in the emergency department, you have a patient who EMS has brought in from a nursing home…who’s excited? Right, nobody is. And they are brought in for a chief complaint of altered mental status. So they’re concerned about sepsis. …
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