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Tag: SAFER Trial

Short Course Antibiotics for Peds CAP: A Systematic Review and Meta-Analysis

by posted December 5, 2022 No Comments

Background: There is a shifting paradigm with persuasive evidence favoring a shorter duration of antibiotics for outpatient management of community-acquired pneumonia (CAP) in children. The SAFER and CAP-IT trials found that short-course antibiotic therapy was not inferior to standard duration …

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Infectious DiseasePediatrics

The SAFER Trial: Pediatric CAP – Amoxicillin 5 days vs 10 days

by posted June 17, 2021 No Comments

Background: The evidence supporting the use of a 10-day course of high-dose amoxicillin to treat community-acquired pneumonia (CAP) in pediatric patients is weak. In addition, medicine is trending towards shorter courses of antibiotics when clinically appropriate. REBEL EM covered a similar …

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Infectious DiseaseThoracic and Respiratory
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