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Tag: NoPAC

Meta-Analysis on Topical TXA for Epistaxis

Background Information: Epistaxis management in the emergency department has historically included topical vasoconstrictors, local anesthetics such as oxymetazoline and phenylephrine and topical fibrinolytic agents such as Tranexamic Acid (TXA). When these topical agents fail, packing, chemical cauterization or surgical ligation …

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Head, Eye, Ear, Nose, and ThroatProcedures and SkillsResuscitation

REBEL Cast Ep97: The NoPAC Trial – TXA for Epistaxis?

Background: Epistaxis is a common Emergency Department (ED) complaint with over 450,000 visits per year and a lifetime incidence of 60% (Gifford 2008, Pallin 2005). Standard anterior epistaxis treatment consists of holding pressure, use of local vasoconstrictors, topical application of …

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Head, Eye, Ear, Nose, and Throat

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