Archive

Tag: Blood Transfusion

Should We Be Switching to Whole Blood Instead of Component Therapy in Hemorrhagic Shock?

Background: Hemorrhage remains as one of the biggest causes of death in trauma patients. Strategies such as permissive hypotension, massive transfusion protocols, avoidance of crystalloids, TXA, and definitive hemorrhage control help decrease mortality in these patients. Empiric component blood transfusion ...

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Hematology and OncologyTrauma

Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (MINT Trial)

Background: Concurrent anemia worsens outcomes in patients that present with acute myocardial infarctions. Transfusions increase the oxygen carrying capacity of blood which can improve the perfusion of at-risk cardiac tissue. However, transfusions are also associated with immunosuppression, thrombotic phenomena, volume ...

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CardiovascularHematology and Oncology

The REALITY Trial: Restrictive vs Liberal Blood Transfusion in Patients with AMI and Anemia

Background: Transfusion thresholds for anemia have large variations in clinical practice.  This is especially true in patients with acute myocardial infarction (AMI).  Part of the reason for this is the lack of high-quality data.  There was a large, randomized trial ...

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Cardiovascular

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