Rebellion21 – “HALT IT” In the Name of Evidence via J Scott Wieters, MD

In this 20-minute presentation from Rebellion in EM 2021, Dr. J Scott Wieters, MD discusses the evidence for and against the use of tranexamic acid for hemorrhage alleviation in gastrointestinal bleeding by doing a critical appraisal of the HALT-IT trial.

Scott Wieters, MD
Emergency Medicine Faculty
Temple Campus Dean
Texas A&M College of Medicine/Baylor Scott & White EM
Twitter: @EMedCoach


  1. Understand clinical pharmacology of TXA
  2. Describe background research in TXA use
  3. Perform critical appraisal of HALT-IT trial
  4. Apply EBM to patients with acute GI bleeding

Clinical Question: Does IV TXA reduce 5d mortality for adult patients with GIB?

For More Thoughts on This Topic Checkout:

Post Peer Reviewed By: Salim R. Rezaie, MD (Twitter: @srrezaie)

Cite this article as: Salim Rezaie, "Rebellion21 – “HALT IT” In the Name of Evidence via J Scott Wieters, MD", REBEL EM blog, September 9, 2021. Available at:

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