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Rebel Category: REBEL Covid-19

BLAZE-1 Final Publication: Monoclonal Antibody Cocktail Part II

Background: One of the many massive challenges of the COVID19 pandemic has been the lack of targeted therapeutics. Extensive efforts have been invested into research with only glimmers of benefit for most drugs. The exception to this has been dexamethasone …

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Infectious Disease

COVID-19 Awake Proning – All Hype?

Background: Facilities around the world have seen surges of COVID-19 pneumonia  patients who have required protracted hospitalizations leading to overwhelmed hospital systems. Awake proning is a practice that was adopted early in the pandemic as a means to avoid, or …

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Infectious DiseaseThoracic and Respiratory

No Evidence that REGN-COV2 (Regeneron) Antibody Cocktail Has Clinical Benefits

Background: Antibodies targeted at the SARS-CoV2 spike protein are an essential part of the body’s immune response to COVID19 infection. The recent emergency use authorization (EUA) Pfizer and Moderna vaccines act by introducing mRNA into the body that instructs cells …

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Infectious Disease

COVID-19 Update: The ChAdOx1 (AstraZeneca) COVID-19 Vaccine

Background Information: With rising cases, an increasing death toll, and a significant strain on hospital systems globally, the COVID-19 pandemic seemed to have no end in sight. The aggressive pursuit of a vaccine has led to multiple clinical trials starting before …

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Infectious Disease

REBEL Cast Ep93: COVID-19 – A Follow Up on Not Intubating Early and ARDSnet

Back in April 2020, on REBEL Cast episode 79 we sat down to discuss COVID-19.  Specifically, we focused on not intubating patients early and why ARDSnet may not be the best ventilator paradigm for patients with COVID-19.  By popular demand, …

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Infectious Disease

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