Archive

Rebel Category: REBEL Covid-19

COVID-19 and Anticoagulation: Full Dose or Prophylactic Dose?

Background: Patients with COVID-19 are at a high risk for the development of venous thromboembolic disease [Link is HERE]. Alveolar capillary microthrombi appear to be 9x more prevalent in patients with COVID-19 compared to H1N1. As a result, enhanced-dose anticoagulation …

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Hematology and Oncology

RECOVERY Trial: The REGN-COV Antibody Cocktail in COVID19

Background: Antibodies targeted at the SARS-CoV2 spike protein are an essential part of the body’s immune response to COVID19 infection. Infection with SARS-CoV2 stimulates the immune system to produce a polyclonal spike protein antibody response in the host. Vaccines have …

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Infectious Disease

COV-BARRIER: Baricitinib in Hospitalized Adults with COVID19

Background: Outside of vaccines, effective pharmaceuticals for COVID19 continue to be evasive. Steroids have been a success (in patients who require supplemental O2) leading to additional studies investigating optimal drug and dose. Despite early excitement, we’ve seen high-quality studies demonstrate …

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Infectious Disease

From Emergency Medicine to Hostage Negotiation

Earlier this year, my home shop began administering the Johnson & Johnson COVID-19 vaccine to patients in the emergency department (ED). Thirteen years of experience in emergency medicine has afforded me many opportunities to counsel patients on lifestyle modifications, death …

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Infectious Disease

LIVE-AIR Trial: What the Heck is Lenzilumab?

Background: We have all seen the wide spectrum of illness caused by COVID-19 ranging from asymptomatic disease on one extreme all the way up to critical illness, acute respiratory disease and ultimately death at the other extreme.  In the most …

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Infectious Disease

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