Critical appraisals and clinical takeaways that separate signal from noise.

The A2B Trial: Are Alpha-2 Agonists Better than Propofol for ICU Sedation?

Does primary sedation with dexmedetomidine or clonidine reduce the time to successful extubation in mechanically ventilated critically ill patients compared to propofol-based sedation?

Neurology

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Healthcare team preparing for rapid sequence intubation with an endotracheal tube and oxygen mask, illustrating rocuronium vs succinylcholine for RSI, awareness, paralysis, and post-intubation sedation.
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