SMART Trial Part 2: Secondary Analysis of Balanced Crystalloids vs Saline in Sepsis
Background: Saline (0.9% sodium chloride) has historically been one of the most common intravenous fluids administered in critically ill adults. However, the supraphysiologic chloride concentration can cause hyperchloremia, metabolic acidosis, renal vasoconstriction and alter immune function. There is nothing normal ...
