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Tag: Hematology

REBEL Core Cast 41.0 – Acute Chest Syndrome

Take Home Points 100k people in US have sickle cell, the majority will at some point develop acute chest syndrome (ACS) The mortality rate per episode is 3-9%, similar to those of STEMI ACS is a syndrome – CXR infiltrate …

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CardiovascularHematology and Oncology

Tranexamic Acid (TXA) for Everything that Bleeds?

Background: TXA is a synthetic lysine derivative that binds with the lysine site on plasminogen and inhibits fibrinolysis.  TXA is not a new drug. Studies from the late 1960s and early 1970s have shown reduced bleeding and need for transfusions in …

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Hematology and Oncology

ANNEXA-4: Andexanet Alfa and Factor Xa Inhibitors

Background: Over the past few years we have seen a surge in the use of oral Factor Xa inhibitors (apixaban, rivaroxaban etc) for anticoagulation.  The reason for this is the ease of use, standard dosing with no levels to check and …

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Hematology and Oncology

Rebellion in EM 2018 – DOAC Reversal by Scott Wieters, MD

The 1stannual Rebellion in EM Clinical Conference took place in San Antonio, TX on May 11th– 13th, 2018.  If you missed out in 2018, the Rebellion is coming back June 28th – 30th, 2019.  Stay up to date as we plan …

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Hematology and Oncology

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