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Tag: Amoxicillin

The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

Background: Many patients report a vague history of penicillin allergy. The vast majority of these self-reported allergies are untrue (< 5%) .  Literature including patients with penicillin allergies also show longer, more complicated hospital courses. Standard practice for identifying errant allergy …

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Allergy and Immunology

The CAP-IT Trial: Amoxicillin Dose and Duration in Children with Community-Acquired Pneumonia

Background/Introduction: The commonly cited duration of antibiotic therapy (7-14 days) for community-acquired pneumonia (CAP) has historically been based on arbitrary timelines extrapolated from a desire to prevent treatment failures and avoid under-treatment rather than evidence-based medicine. Even the original literature on …

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Infectious DiseasePediatrics

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