REBEL Core Cast 62.0 – Hemophilia

Take Home Points

  • Infuse factor first, investigate later
  • Treat when bleeding is suspected, not confirmed. Have a low threshold!
  • It is better to over treat than undertreat. Give full dose when in doubt
    • Factor 8 = 50U/kg
    • Factor 9 = 100 U/kg
  • Beware of hidden bleeds (brain, retroperitoneal, deep muscles)
  • If patient has inhibitors, or no factor available you may use
    • Activated PCC (FEIBA) = 80 -100U/kg
    • Recombinant factor 7a = 90 mcg/kg

REBEL Core Cast 62.0 – Hemophilia

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Post Peer Reviewed By: Salim R. Rezaie, MD (Twitter: @srrezaie)

Cite this article as: Anand Swaminathan, "REBEL Core Cast 62.0 – Hemophilia", REBEL EM blog, July 28, 2021. Available at:
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Anand Swaminathan

Clinical Assistant Professor of Emergency Medicine at St. Joe's Regional Medical Center (Paterson, NJ)
REBEL EM Associate Editor and Author

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