Archive

Medical Category: Allergy and Immunology

Clinical Conundrums: Should I Pretreat Patients with Contrast Allergy Prior to IV Contrast Administration?

Bottom Line Up Top: Pretreatment is ineffective and unnecessary as it does not significantly reduce the risk of serious adverse reactions to contrast. Pretreatment should not delay imaging required for definitive diagnosis.  Clinical Scenario: A 65 year-old woman presents with ...

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Allergy and Immunology

Clinical Conundrums: How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis?

How Long Should We Monitor After Giving IM Epinephrine for Anaphylaxis? Bottom Line Up Top: After prompt recognition and appropriate treatment with IM epinephrine, the risk of biphasic reactions are exceedingly low. There is no set observation time to monitor ...

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Allergy and Immunology

Rosh Review EM Scholar Monthly Question

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Allergy and ImmunologyHead, Eye, Ear, Nose, and Throat

REBEL Core Cast 108.0 – Angioedema

Take Home Points: Airway management is paramount; expect a challenging intubation and consider controlling the airway early if there is apparent airway compromise. Understanding the cause of angioedema (mast cell vs. bradykinin mediated) helps dictate directed management. Urticaria and pruritus ...

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Allergy and Immunology

The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

Background: Many patients report a vague history of penicillin allergy. The vast majority of these self-reported allergies are untrue (< 5%) .  Literature including patients with penicillin allergies also show longer, more complicated hospital courses. Standard practice for identifying errant allergy ...

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Allergy and Immunology

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