April 2015 REBELCast

06 Apr
April 6, 2015

April 2015 REBELCastWelcome to the April 2015 REBELCast, where Swami, Matt, and I are going to tackle a couple of articles just published this year. Today we are going to specifically tackle:

  • Topic #1: Basic Life Support (BLS) vs Advanced Cardiac Life Support (ACLS) in Out of Hospital Cardiac Arrest (OHCA)
  • Topic #2: PROMISE Trial – Anatomic vs Functional Testing for Coronary Artery Disease (CAD)

April 2015 REBELCast Podcast

Click here for Direct Download of Podcast

What clinical questions will be covered in the April 2015 REBELCast?

  • Question #1: Does Advanced Cardiac Life Support (ACLS) or Basic Life Support (BLS) have larger beneficial effects on outcomes for Out of Hospital Cardiac Arrest (OHCA)?
  • Question #2: Does anatomic testing with coronary computed tomographic angiography (CCTA) result in improved health outcomes over functional testing in symptomatic patients with suspected CAD?


What specific articles will we be covering?

  • Article #1: Saghavi P et al. Outcomes After Out-of-Hospital Cardiac Arrest Treated by Basic vs Advanced Life Support. JAMA Intern Med 2015; 175 (2): 196 – 204 (25419698)
  • Article #2: Douglas PS et al. Outcomes of Anatomic versus Functional Testing for Coronary Artery Disease. NEJM 2015 [epub ahead of print] (25773919)


What is the clinical bottom line for the above clinical questions:

  • Bottom Line #1: Patients with OHCA who receive BLS have a higher survival to hospital discharge, survival to 90days, and more have better neurologic functioning vs patients who receive ACLS
  • Bottom Line #2: An initial strategy of using CCTA for noninvasive testing in symptomatic patients with suspected CAD is not associated with better clinical outcomes compared to functional testing over median follow-up of two years. It was, however, associated with higher radiation exposure and downstream testing.

March 2015 REBELCast Show Notes

Word Document: REBELCast April 2015 Show Notes
PDF: REBELCast April 2015 Show Notes

For more on the above topics checkout:




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Salim Rezaie

Emergency Physician at Greater San Antonio Emergency Physicians (GSEP)
Creator & Founder of R.E.B.E.L. EM
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  1. […] trial, called PROMISE, also evaluated anatomic CCTA vs functional stress testing in greater than 10,000 patients with […]

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