Buprenorphine Archives - REBEL EM - Emergency Medicine Blog

REBEL Cast Ep117: Low Dose vs Standard Dose Take-Home Buprenorphine From the ED

by Tara Persaud Holmes, MD, MBA posted June 5, 2023 No Comments

Background Information: Opioid overdose deaths have been increasing in the past twenty years. The national number of overdose deaths from any opioid has increased 62.5% from 2019 to 2021 (from 48,000 to 81,400 annual deaths), which includes prescription opioids (natural and …

Toxicology

REBEL Cast Ep102: High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder

by Cara Borelli DO posted November 8, 2021 No Comments

Background information: Buprenorphine and buprenorphine-containing medications are being used in emergency departments for treatment of patients with opioid use disorder (1). Buprenorphine is a high-affinity partial agonist of the μ-opioid receptor. Buprenorphine has a higher affinity for the μ-opioid receptor …

Toxicology