Balanced Crystalloids Archives - REBEL EM

REBEL Cast Ep108: The PLUS Trial – Balanced vs Unbalanced Fluids in the Critically Ill

by Salim Rezaie posted March 10, 2022 No Comments

Background: In the past few years there has been a growing debate between the use of balanced multielectrolyte solutions (BMES) and saline in the critically ill (See the “for more about this topic” section below). Recent research has yielded inconsistent …

Endocrine, Metabolic, Fluid, and Electrolytes

SMART Trial Part 2: Secondary Analysis of Balanced Crystalloids vs Saline in Sepsis

by Salim Rezaie posted December 5, 2019 No Comments

Background: Saline (0.9% sodium chloride) has historically been one of the most common intravenous fluids administered in critically ill adults. However, the supraphysiologic chloride concentration can cause hyperchloremia, metabolic acidosis, renal vasoconstriction and alter immune function. There is nothing normal …

Endocrine, Metabolic, Fluid, and Electrolytes