Archive

Tag: allergy

The PALACE Trial: Direct Oral PCN Challenge in Patients with Low-Risk PCN Allergy?

Background: Many patients report a vague history of penicillin allergy. The vast majority of these self-reported allergies are untrue (< 5%) .  Literature including patients with penicillin allergies also show longer, more complicated hospital courses. Standard practice for identifying errant allergy …

Read More
Allergy and Immunology

Cetirizine Vs Diphenhydramine For the Treatment of Acute Urticaria in the ED

Background: Diphenhydramine, a first-generation antihistamine, is the most common pharmacologic agent used to treat acute allergic reactions. Despite being highly effective in treating acute allergic reactions, first-generation H1 antihistamines cross the blood-brain barrier and bind to H1 receptors, which can …

Read More
Allergy and Immunology

Sponsored