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Tag: ACS

REBEL Core Cast 113.0 – ACS Therapies and Management

Take Home Points: All STEMIs should be loaded with dual antiplatelet therapy. Prasugrel (Effient) is avoided as there is an increase in bleeding complications if the patient requires a CABG. NSTEMI cases can be challenging to manage. Consult Cardiology early …

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Cardiovascular

REBEL Cast Ep114: High Flow O2, Suspected ACS, and Mortality?

Background: Historically, we have treated acute coronary syndrome with supplemental oxygen regardless of the patient’s oxygen saturation.  This intervention was based on the belief that pushing the patient’s PaO2 to supra therapeutic levels would increase O2 delivery to ischemic myocardium …

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Cardiovascular

Retrospective Validation of High-Sensitivity Troponin with 5 Clinical Decision Instruments

Background: Chest pain is the second most common reason for presentation to the emergency department (ED) and accounts for nearly 6.5 million visits each year. [1] Management often requires the utilization of clinical gestalt, laboratory analysis, diagnostic imaging, and clinical prediction …

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Cardiovascular

ISAR-REACT 5 Trial: Ticagrelor vs Prasugrel in ACS

Background: In patients presenting to the ED with acute coronary syndrome (ACS), dual antiplatelet therapy is the current standard treatment.  This typically consists of aspirin and an adenosine diphosphate receptor antagonist.  It is fairly well understood that prasugrel and ticagrelor …

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Cardiovascular

Can Emergency Physicians Use Clinical Gestalt to Predict Acute Coronary Syndrome?

Background: Chest pain is a common chief complaint the Emergency Department, and the differential diagnosis includes life-threatening conditions from several organ systems including cardiac, pulmonary, and gastrointestinal, in addition to more benign etiologies. Historically, despite most patients not having acute …

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Cardiovascular

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