Critical appraisals and clinical takeaways that separate signal from noise.

The TASC Trial: Therapeutic vs Prophylactic Anticoagulation for Acute Chest Syndrome

In adults with sickle cell disease hospitalized for acute chest syndrome (ACS) without pulmonary artery macrothrombosis, does therapeutic-dose anticoagulation with tinzaparin shorten ACS duration compared with prophylactic-dose anticoagulation?

Hematology and Oncology
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