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REBEL Core Cast 108.0 – Angioedema

…vs. bradykinin mediated) helps dictate directed management. Urticaria and pruritus = MAST CELL mediated, which is treated like a standard allergic reaction. REBEL Core Cast 108.0 – Angioedema https://traffic.libsyn.com/secure/rebelcast/REBEL_Core_Angioedema.mp3 Click…

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Icatibant Doesn’t Improve Outcomes in ACE-I Induced Angioedema

…intervention. Patients with non-ACE-I induced angioedema (i.e. hereditary angioedema, allergic angioedema, acquired angioedema), anaphylaxis, trauma, abscess or infection, local tumor, postoperative/postradiogenic edema, salivary gland disorders, acute urticaria. Primary Results: 147…

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tPA-Associated Angioedema

angioedema can be variable, but once the infusion of tPA has completed, the risk angioedema greatly decreases. The majority of tPA associated angioedema are orolingual versions. Symptoms may be asymmetric…

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Industry Sponsored Trials and  Entresto in CHF

…(SBP <100mmHg at screening or <95mmHg at randomization) eGFR <30mL/min/1.73m2 Serum potassium level of >5.2mmol/L at screening (or above 5.4 mmol/L at randomization) History of angioedema Results (Trial stopped early…

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