Background: At my shop we have changed wholesale to the use of tenecteplase over alteplase for acute ischemic stroke meeting criteria for thrombolytic therapy. This was based on a systematic review and meta-analysis of 6 RCTs and 2 observational trials …
Background: While the effects of stroke can be both debilitating and devastating, the benefit of certain treatments have not always been clear and the data supporting them are fraught with controversy. Reanalysis of the two trials demonstrating the benefit of thrombolytics …
In this episode of REBEL Cast, Anand Swaminathan and I sit down to discuss the utility of thrombolysis prior to Endovascular therapy for LVO acute ischemic stroke. The discussion is broken up into two potential scenarios: Not all facilities are …
In this 15-minute lecture from Rebellion in EM 2021, George Willis, MD discusses acute ischemic stroke and the evidence base for and against thrombolysis.
In this 9 minute video from day 2 of Rebellion in EM 2021, I go over the evidence for advanced imaging use in acute ischemic stroke of unknown time of onset to help guide treatment with intravenous alteplase.
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