Critical appraisals and clinical takeaways that separate signal from noise.

Effect of Sepsis Bundle (SEP-1) Compliance and Implementation on Mortality

Is there any moderate or high-level evidence that SEP-1 compliance and/or implementation is associated with improvement in sepsis mortality?

Infectious DiseaseResuscitation

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Healthcare team preparing for rapid sequence intubation with an endotracheal tube and oxygen mask, illustrating rocuronium vs succinylcholine for RSI, awareness, paralysis, and post-intubation sedation.
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