Archive

Author: Salim Rezaie

REBEL Cast Ep72: Systemic Alteplase in Stroke Mimics is Safe?

Background: Currently, alteplase is the mainstay of treatment of acute ischemic stroke.  Advocates of alteplase suggest that the benefit of alteplase is greatest when given early and declines with increasing time from stroke symptom onset (i.e. time is brain).  Therefore, the …

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Neurology

Slide Design Tip: How Does an Eyedropper Improve Slides?

Have you ever wondered how to get your text color to match your image color?  It’s not hard and can make a good slide become an amazing slide.  Matching colors make consistent, professional-looking PowerPoint or Keynote slides.  The steps to …

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Can a Novel Intervention Improve Patient Follow-Up After ED Discharge?

Background: Follow-up with a primary care (PC) provider is an important part of healthcare.  Many countries have a robust outpatient system, and the US is no different. However, in the US, there are many challenges to follow up including: appointment availability, insurance …

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Another RCT of the Modified Valsalva Maneuver

Background: In patients with hemodynamically stable supraventricular tachycardia (SVT), vagal maneuvers are the traditional first step in management.  There are several  vagal techniques in the literature which include, standard valsalva maneuver (sVM), modified Valsalva maneuver (mVM), and carotid sinus massage (CSM). …

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Cardiovascular

CRASH-3: TXA for ICH?

Background: Evidence from the CRASH-2 trial showed an absolute reduction in mortality of 1.5% (NNT = 67) in patients with extracranial bleeding treated with tranexamic acid  (TXA) within 3 hours of injury. However, CRASH-2 did not answer the question of …

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Trauma

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