Rebel Category: REBEL CME

REBEL Cast Episode 66: The COACT Trial – Coronary Angiography After Cardiac Arrest without STEMI

Background: Post-ROSC care is a multifaceted endeavor that includes targeted temperature management (TTM), vital-organ support, and treatment of the underlying cause of arrest. One of the most common causes of cardiac arrest is acute coronary syndrome.  Current European and American guidelines …

Read More

The Great Debate Between Balanced and Unbalanced Crystalloids Continues

Background: Although the debate over balanced (i.e. lactated ringers, PlasmaLyte) vs unbalanced (i.e. 0.9% saline) crystalloids has not been settled, fluid resuscitation continues to be a fundamental therapy given to critically ill patients.  0.9% saline is one of the most common …

Read More
Endocrine, Metabolic, Fluid, and Electrolytes

Tranexamic Acid (TXA) for Everything that Bleeds?

Background: TXA is a synthetic lysine derivative that binds with the lysine site on plasminogen and inhibits fibrinolysis.  TXA is not a new drug. Studies from the late 1960s and early 1970s have shown reduced bleeding and need for transfusions in …

Read More
Hematology and Oncology


Knowledge translation (KT) is the process involved in moving research from the laboratory bench, research journals, and academic conferences to the hands of providers who can put it to practical use at the bedside or in the prehospital environment. REBEL …

Read More

High Flow Nasal Cannula (HFNC) – Part 1: How It Works

The use of heated and humidified high flow nasal cannula (HFNC) has become increasingly popular in the treatment of patients with acute respiratory failure through all age groups.  I first started using it as a pediatric intensive care fellow, but …

Read More
Thoracic and Respiratory