The Novel Coronavirus 2019, was first reported on in Wuhan, China in late December 2019.  The outbreak was declared a public health emergency of international concern in January 2020 and on March 11th, 2020, the outbreak was declared a global pandemic.  The spread of this virus is now global with lots of media attention.  The virus has been named SARS-CoV-2 and the disease it causes has become known as coronavirus disease 2019 (COVID-19). This new outbreak has been producing lots of hysteria and false truths being spread, however the data surrounding the biology, epidemiology, and clinical characteristics are growing daily, making this a moving target.

REBEL COVID-19

will serve as a summary of what is currently known, how to screen, when to test, and how to prevent spread, and any new data/information on COVID-19.

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  • REBEL Covid-19
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  • REBEL Covid-19

COV-BARRIER Addendum Study: Baricitinib in ECMO/Mechanically Ventilated Patients with COVID-19

Background:  Despite access to vaccines in developed countries, COVID19 remains a nimble and persistent foe. While case counts wax and wane the virus continues to spread and mutate. The rapid development of vaccines has been helpful but the distribution across …

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Infectious DiseaseThoracic and Respiratory

The HEP-COVID Trial: Therapeutic Anticoagulation in Non-Critically Ill COVID-19 Patients

Background: Patients with COVID-19 are at increased risk from thromboembolic phenomena. Patient-specific factors such as comorbidities and immobility have been linked to thrombosis. Disease-specific factors such as virus-induced endothelial changes and cytokine storm may also be triggers. Furthermore, patients with elevated …

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Hematology and OncologyInfectious DiseaseThoracic and Respiratory

REBEL Cast Ep103: Outpatient COVID-19 Therapy

I was fortunate enough to record a podcast on Rob Orman’s, Stimulus podcast on Oct 14th, 2021.  We both felt it was an important enough topic that we should post it on both his and my site.  The treatment of …

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Infectious Disease

The DisCoVeRy Trial: Remdesivir in COVID-19 – An Expensive Version of Tamiflu?

Background: Since the beginning of the pandemic, hundreds of trials have been  performed looking at medications with the potential to be repurposed for use against COVID19. To date, no antiviral medications directed at SARS-CoV-2 have shown any convincing evidence of …

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Infectious Disease

The TOGETHER Trial: COVID-19 and Fluvoxamine Take Two

Background: Despite having a safe and effective set of vaccines for COVID-19, there have been some low resource countries in which it has been very challenging in getting the vaccine allocated.  Therefore, identifying an inexpensive, widely available, and effective therapy …

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Awake Proning for COVID-19 Acute Hypoxemic Respiratory Failure

Background: Awake prone positioning was an intervention adopted early in the COVID-19 pandemic for patients with hypoxemic respiratory failure.  Unfortunately, many early trials were not powered to show improvements in oxygenation, escalation of respiratory support, or mortality. The one meta-analysis …

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ResuscitationThoracic and Respiratory

It’s All About Risk: BNT162b2 mRNA COVID-19 Vaccination vs Natural Infection

Background: The world has been involved in mass vaccination efforts for the last nine months. Since the vaccines were approved, billions of doses have been administered.  Initial trials showed the COVID-19 vaccines to be efficacious and safe.   However, assessing vaccine …

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Infectious Disease

RECOVERY RS: CPAP vs HFNO vs Conventional Oxygen Therapy in COVID-19

Background: Much of the last two years has been both a complete blur and indelibly memorable. This dichotomy is encapsulated by the rapid changes and updates in medical management and hospital algorithms coupled with the memories of frightened faces of …

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Thoracic and Respiratory

Rebellion21: Good Vibrations with Corona – Using POCUS in the COVID Era via Eric Chin, MD

In this 18-minute presentation from Rebellion in EM 2021, Dr. Eric Chin, MD describes the role of point-of-care ultrasound in the evaluation of a COVID patient. Much of this talk focuses on thoracic and lung ultrasound.

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Infectious DiseaseProcedures and SkillsThoracic and Respiratory
PRIEST Score rebel em

The PRIEST Score: Predicting Adverse Outcomes in COVID-19

Background: The limited availability of rapid tests with sufficient sensitivity has been an issue since the beginning of the pandemic.  Therefore, multiple clinical decision scores have been studied to overcome this issue. The addition of laboratory and radiological information can …

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Infectious Disease

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