Archive

Tag: Infectious Disease

Omadacycline, the NEJM and Non-Inferiority Studies

Introduction: The production and release of new antibiotics is rare and should be celebrated by clinicians. As antibiotic resistance continues to mount, our options narrow and, in turn, our patients suffer. Recently, the NEJM published two articles on a new …

Read More
Infectious Disease

IDSA Guideline on Seasonal Influenza Management 2018

Article: Uyeki TM et al. Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis 2018. PMID: 30566567 Background: Influenza is an Emergency Department …

Read More
Infectious Disease

Baloxavir (Xofluza), a New Influenza Anti-Viral Medication is FDA Approved, But Does it Work?

Background: On October 24th, 2018, Roche, the maker of oseltamivir, announced that the US Food and Drug Administration (FDA) approved Xofluza (baloxavir marboxil) for the treatment of acute, uncomplicated influenza in people 12 years of age and older. Historically, there …

Read More
Infectious Disease

The Tamiflu Debacle

Background:  Oseltamivir (Tamiflu), a neuraminidase inhibitor, was approved by the FDA in 1999.  The majority of the evidence supporting the use of the medication came from trials funded by Roche, the maker of the drug. Safety issues with the drug …

Read More
Infectious Disease

Do Patients with Strep Throat Need to Be Treated with Antibiotics?

Background: Streptococcal pharyngitis is a common presentation to primary care and Emergency Department physicians. Every year, 10 million patients in the United States are treated with antibiotics for pharyngitis. However, less than 10% of these patients actually have strep pharyngitis (Barnett …

Read More
Infectious Disease

Sponsored