Tag: CVA

The DIRECT-MT Trial: Are Systemic Lytics Necessary in LVO Treatment?

by Anand Swaminathan posted May 14, 2020 No Comments

Background: The publication of the MR CLEAN trial in January 2015 changed the face of ischemic stroke care. This was the first study demonstrating a benefit to endovascular treatment of a specific subset of ischemic stroke patients: those with a …

Neurology

The ENCHANTED Trial: Is Low-Dose the Right Dose for Intravenous tPA in Acute Ischemic Stroke?

by Anand Swaminathan posted May 26, 2016 No Comments

Background: Despite continued debate on the efficacy of alteplase (tPA), it currently remains one of the major interventions directed at patients presenting with acute ischemic stroke. The current standard dose of the drug is 0.9 mg/kg given over 1 hour. …

Neurology