Archive for category: Pharmacology

More Trials Showing Harm of Opioids in ACS…or do They?

22 Feb
February 22, 2018

Background: Typical medical treatment of ACS patients include dual antiplatelet therapy (DAPT) and revascularization with primary percutaneous coronary intervention (PPCI).  Nitroglycerin is first line therapy in the treatment of pain in ACS with morphine as a common adjunct. Morphine helps relieve pain which decreases catecholamines and oxygen demand.  We have written about the use of […]

REBEL Cast Ep 43: Pain Control and Opioid Sparing Options in the ED

08 Jan
January 8, 2018

Background: In the United States we are not only seeing an opioid epidemic but also a shortage of IV opioid agents. For both reasons, it is important to find non-opioid options for common pain complaints seen in the ED.  Changing prescribing practices is difficult but an important step in minimizing opioid usage.  Current research suggests […]

Clinical Pearls from ACEP 2017 – Washington D.C.

09 Nov
November 9, 2017

This year ACEP 2017 took place in Washington D.C. from Oct. 29th – Nov 1st, 2017.   There were lots of amazing speakers and topics as was evidenced by the eruption of everyone’s twitter feeds with the #ACEP17 hashtag.  I was fortunate enough to attend this amazing conference and approached by several attendees if I would […]

Acetaminophen vs. Diclofenac vs. Combo for Acute MSK Pain

02 Nov
November 2, 2017

Background: Acute, minor musculoskeletal injuries (i.e. non-fracture or dislocations) are frequently seen in the Emergency Department. Aside from ruling out a more severe injury, management often focuses on pain relief or mitigation of pain. Though many analgesic agents exist, acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for this indication. Both have important side […]

REBEL Cast Episode 40: Research From the Past Year – Pain Control

20 Oct
October 20, 2017

Welcome back to Episode 40 of REBEL Cast. We have taken some time off but don’t worry, we are back.  In this episode, we will be discussing some studies from the past year that caught our attention, dealing with pain control.  With the hundreds of journals in EM/CC and the thousands of publications it is […]

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