Archive for category: Endocrinology

Any Benefit to Sodium Bicarbonate in DKA?

12 May
May 12, 2014

In a prior post, we discussed the use of an initial insulin bolus in the management of diabetic ketoacidosis (DKA).  Today we will address another facet of DKA management, for which there is less than optimal evidence and that is: Any benefit to sodium bicarbonate in DKA?  Consensus guidelines for the management of DKA recommended […]

ECG Changes of Hyperkalemia

17 Apr
April 17, 2014

Hyperkalemia is an electrolyte abnormality seen in the emergency department as well as in hospitalized patients and it can be associated with adverse clinical outcomes and death if not treated appropriately. It is important to remember that the electrophysiologic effects of hyperkalemia are directly proportional to both the absolute plasma potassium and its rate of […]

Is There Any Benefit to an Initial Insulin Bolus in Diabetic Ketoacidosis?

27 Mar
March 27, 2014

Diabetic ketoacidosis (DKA) is a common endocrine emergency encountered in the emergency department.  DKA associated mortality is relatively low in adults, but in children with type 1 diabetes, the elderly, and adults with concomitant illnesses have a mortality rate is > 5% .  Guidelines for the management of hyperglycemic crisis in adults provide recommendations for intravenous […]