Archive

Author: Salim Rezaie

REBEL Cast Ep70 – Time to Antibiotics in Sepsis

Background: Antibiotics are one of the cornerstones of therapy in the treatment of sepsis/septic shock, however according to the Surviving Sepsis Campaign (SSC) guidelines, time to antibiotics is a core measure, though there is weak evidence in support of this.  Most …

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Infectious Disease

RESTART: REstart or STop Antithrombotics Randomized Trial

Background:  In patients with ICH, antiplatelet therapy is withheld due to the perceived risk of hematoma expansion.  Often, these medications are either not restarted or there is prolonged delays until they are restarted, but the risk of occlusive vascular events …

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Hematology and Oncology

Should We Not Be Using IVC Filters in Trauma Patients?

Background: Trauma patients can be a rather difficult patient population to treat with multiple ongoing issues.  There is always a balance of hemorrhage control vs prophylaxis for venous thromboembolism (VTE), as both can cause increased morbidity and mortality.  One method to …

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Trauma

Dosing and Timing of Epinephrine in OHCA

Background: Epinephrine (adrenaline) remains a central part of management of OHCA in ACLS guidelines. Recent studies (i.e. PARAMEDIC-2) have raised concerns about the efficacy and possible deleterious effects of epinephrine on both overall survival and long-term neurological outcomes. Other observational trials have …

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Resuscitation

REBEL Cast Episode 69: Rebellion in EM Day 3 Speaker Summaries with Andy Little

This is a special edition REBEL Cast done by my good friend Andy Little, DO (Twitter: @andylittle).  As I was busy running the 2nd annual Rebellion in EM clinical conference, Andy was able to sit down with the speakers to …

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